Hairy and Enhancer of Split 5 (HES5) (Middle Region) Peptide
Quick Overview for Hairy and Enhancer of Split 5 (HES5) (Middle Region) Peptide (ABIN977945)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- AASDTQMKLL YHFQRPPAAP AAPAKEPKAP GAAPPPALSA KATAAAAAAH
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HES5 Antibody(ARP50367_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HES5 (Hairy and Enhancer of Split 5 (HES5))
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Background
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This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.
Alias Symbols: bHLHb38
Protein Interaction Partner: JAK2,STAT3
Protein Size: 166 -
Molecular Weight
- 18 kDa
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Gene ID
- 388585
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NCBI Accession
- NM_001010926, NP_001010926
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UniProt
- Q5TA89
Target
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